TARGETED AGENTS AND IMMUNOTHERAPIES IN CRC
Introduction
Targeted agents for the treatment of CRC target specific genetic mutations while immunotherapies target immunological mechanisms that cancer cells use to survive and proliferate. In this chapter, we'll explore the targeted agents and immunotherapies that are being used to fight advanced colorectal cancers.
Chapter 4
Topic 1
Biomarker, Biologic and Immunotherapies
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Topic 2
Pathway Overview
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Topic 3
Angiogenesis and VEGF in CRC
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Topic 4
Bevacizumab (Avastin®)
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Topic 5
Ziv-aflibercept (Zaltrap®)
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Topic 6
Ramucirumab (Cyramza®)
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Topic 7
The EGFR Pathway in CRC
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Topic 8
Cetuximab (Erbitux®)
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Topic 9
Panitumumab (Vectibix®)
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Topic 10
Multikinase Inhibitors and Regorafenib (Stivarga®)
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